Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cntn2  contactin 2   (Synonyms: axonin, D130012K04Rik, TAG1, TAG-1, Tax)
Results	Reference
1	J:186055 Ashique AM, Choe Y, Karlen M, May SR, Phamluong K, Solloway MJ, Ericson J, Peterson AS, The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal. 2009;2(95):ra70
1	J:178481 Bachy I, Franck MC, Li L, Abdo H, Pattyn A, Ernfors P, The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons. Dev Biol. 2011 Dec 1;360(1):77-86
1	J:69624 Bermingham NA, Hassan BA, Wang VY, Fernandez M, Banfi S, Bellen HJ, Fritzsch B, Zoghbi HY, Proprioceptor pathway development is dependent on math1. Neuron. 2001 May;30(2):411-22
1	J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7
1	J:218594 Butler SJ, Bronner ME, From classical to current: Analyzing peripheral nervous system and spinal cord lineage and fate. Dev Biol. 2015 Feb 15;398(2):135-146
1	J:83462 Butler SJ, Dodd J, A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons. Neuron. 2003 May 8;38(3):389-401
1	J:82736 Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M, The Morphogen Sonic Hedgehog Is an Axonal Chemoattractant that Collaborates with Netrin-1 in Midline Axon Guidance. Cell. 2003 Apr 4;113(1):11-23
1	J:60158 Chen H, Bagri A, Zupicich JA, Zou Y, Stoeckli E, Pleasure SJ, Lowenstein DH, Skarnes WC, Chedotal A, Tessier-Lavigne M, Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron. 2000 Jan;25(1):43-56
1*	J:332104 Company V, Murcia-Ramon R, Andreu-Cervera A, Aracil-Pastor P, Almagro-Garcia F, Martinez S, Echevarria D, Puelles E, Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus. Dev Dyn. 2022 Nov;251(11):1834-1847
1	J:336857 Dailey-Krempel B, Martin AL, Jo HN, Junge HJ, Chen Z, A tug of war between DCC and ROBO1 signaling during commissural axon guidance. Cell Rep. 2023 May 30;42(5):112455
1	J:39765 Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA, Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature. 1997 Apr 24;386(6627):796-804
1	J:278143 Ferent J, Giguere F, Jolicoeur C, Morin S, Michaud JF, Makihara S, Yam PT, Cayouette M, Charron F, Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance. Neuron. 2019 Jun 19;102(6):1157-1171.e5
1	J:132880 Gore BB, Wong KG, Tessier-Lavigne M, Stem cell factor functions as an outgrowth-promoting factor to enable axon exit from the midline intermediate target. Neuron. 2008 Feb 28;57(4):501-10
1	J:290598 Gorla M, Santiago C, Chaudhari K, Layman AAK, Oliver PM, Bashaw GJ, Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019 Mar 19;26(12):3298-3312.e4
1	J:212572 Haddick PC, Tom I, Luis E, Quinones G, Wranik BJ, Ramani SR, Stephan JP, Tessier-Lavigne M, Gonzalez LC, Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor. PLoS One. 2014;9(1):e84823
1*	J:185870 Hazen VM, Andrews MG, Umans L, Crenshaw EB 3rd, Zwijsen A, Butler SJ, BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord. Dev Biol. 2012 Jul 15;367(2):216-27
1	J:227404 Hernandez-Enriquez B, Wu Z, Martinez E, Olsen O, Kaprielian Z, Maness PF, Yoshida Y, Tessier-Lavigne M, Tran TS, Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing. Genes Dev. 2015 Dec 15;29(24):2617-32
1	J:144923 Islam SM, Shinmyo Y, Okafuji T, Su Y, Naser IB, Ahmed G, Zhang S, Chen S, Ohta K, Kiyonari H, Abe T, Tanaka S, Nishinakamura R, Terashima T, Kitamura T, Tanaka H, Draxin, a repulsive guidance protein for spinal cord and forebrain commissures. Science. 2009 Jan 16;323(5912):388-93
1	J:150348 Iulianella A, Sharma M, Vanden Heuvel GB, Trainor PA, Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord. Development. 2009 Jul;136(14):2329-34
1	J:162558 Jaworski A, Long H, Tessier-Lavigne M, Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance. J Neurosci. 2010 Jul 14;30(28):9445-53
1*	J:227045 Jaworski A, Tom I, Tong RK, Gildea HK, Koch AW, Gonzalez LC, Tessier-Lavigne M, Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2. Science. 2015 Nov 20;350(6263):961-5
1	J:279776 Johnson V, Junge HJ, Chen Z, Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2. Elife. 2019 Aug 8;8:e46042
1	J:283402 Kastriti ME, Stratigi A, Mariatos D, Theodosiou M, Savvaki M, Kavkova M, Theodorakis K, Vidaki M, Zikmund T, Kaiser J, Adameyko I, Karagogeos D, Ablation of CNTN2+ Pyramidal Neurons During Development Results in Defects in Neocortical Size and Axonal Tract Formation. Front Cell Neurosci. 2019;13:454
1	J:257400 Kim KT, Kim N, Kim HK, Lee H, Gruner HN, Gergics P, Park C, Mastick GS, Park HC, Song MR, ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons. Sci Rep. 2016 Nov 7;6:36491
1*	J:272623 Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, Mishima T, Chen X, Tsuboi Y, Rao Y, Yuasa-Kawada J, Wu JY, A crucial role for Arf6 in the response of commissural axons to Slit. Development. 2019 Feb 4;146(3):dev172106
1	J:224947 Lane C, Qi J, Fawcett JP, NCK is critical for the development of deleted in colorectal cancer (DCC) sensitive spinal circuits. J Neurochem. 2015 Sep;134(6):1008-14
1	J:208339 Laumonnerie C, Da Silva RV, Kania A, Wilson SI, Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system. Development. 2014 Feb;141(3):594-603
1	J:272124 Laumonnerie C, Tong YG, Alstermark H, Wilson SI, Commissural axonal corridors instruct neuronal migration in the mouse spinal cord. Nat Commun. 2015 May 11;6:7028
1	J:234106 Leggere JC, Saito Y, Darnell RB, Tessier-Lavigne M, Junge HJ, Chen Z, NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Elife. 2016;5:e14264
1	J:159129 Liu G, Li W, Wang L, Kar A, Guan KL, Rao Y, Wu JY, DSCAM functions as a netrin receptor in commissural axon pathfinding. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2951-6
1	J:89780 Long H, Sabatier C, Ma L, Plump A, Yuan W, Ornitz DM, Tamada A, Murakami F, Goodman CS, Tessier-Lavigne M, Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron. 2004 Apr 22;42(2):213-23
1*	J:69842 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol. 2001 May 21;434(1):13-28
1	J:86902 Lyuksyutova AI, Lu CC, Milanesio N, King LA, Guo N, Wang Y, Nathans J, Tessier-Lavigne M, Zou Y, Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science. 2003 Dec 12;302(5652):1984-8
1	J:122797 Ma L, Tessier-Lavigne M, Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons. J Neurosci. 2007 Jun 20;27(25):6843-51
1	J:123223 Markham K, Schuurmans C, Weiss S, STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci. 2007 Jun;35(2):272-82
1	J:121105 Matsumoto Y, Irie F, Inatani M, Tessier-Lavigne M, Yamaguchi Y, Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate. J Neurosci. 2007 Apr 18;27(16):4342-50
1	J:92188 Millen KJ, Millonig JH, Hatten ME, Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse. Dev Biol. 2004 Jun 15;270(2):382-92
1*	J:48401 Minabe-Saegusa C, Saegusa H, Tsukahara M, Noguchi S, Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach. Dev Growth Differ. 1998 Jun;40(3):343-53
1	J:115577 Okada A, Charron F, Morin S, Shin DS, Wong K, Fabre PJ, Tessier-Lavigne M, McConnell SK, Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature. 2006 Nov 16;444(7117):369-73
1	J:204152 Onishi K, Shafer B, Lo C, Tissir F, Goffinet AM, Zou Y, Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. J Neurosci. 2013 Dec 4;33(49):19071-85
1	J:179910 Palmesino E, Haddick PC, Tessier-Lavigne M, Kania A, Genetic Analysis of DSCAM's Role as a Netrin-1 Receptor in Vertebrates. J Neurosci. 2012 Jan 11;32(2):411-6
1	J:156777 Parra LM, Zou Y, Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing. Nat Neurosci. 2010 Jan;13(1):29-35
1*	J:259672 Peng J, Ferent J, Li Q, Liu M, Da Silva RV, Zeilhofer HU, Kania A, Zhang Y, Charron F, Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait. Dev Dyn. 2018 Apr;247(4):620-629
1	J:70191 Pierani A, Moran-Rivard L, Sunshine MJ, Littman DR, Goulding M, Jessell TM, Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron. 2001 Feb;29(2):367-84
1*	J:190417 Rama N, Goldschneider D, Corset V, Lambert J, Pays L, Mehlen P, Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth. J Biol Chem. 2012 Aug 24;287(35):30014-23
1	J:89438 Sabatier C, Plump AS, Le Ma, Brose K, Tamada A, Murakami F, Lee EY, Tessier-Lavigne M, The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons. Cell. 2004 Apr 16;117(2):157-69
1	J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87
1	J:153212 Schmidt H, Stonkute A, Juttner R, Koesling D, Friebe A, Rathjen FG, C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16847-52
1*	J:37125 Serafini T, Colamarino SA, Leonardo ED, Wang H, Beddington R, Skarnes WC, Tessier-Lavigne M, Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell. 1996 Dec 13;87(6):1001-14
1	J:169765 Shafer B, Onishi K, Lo C, Colakoglu G, Zou Y, Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell. 2011 Feb 15;20(2):177-91
1	J:287691 Suter TACS, Blagburn SV, Fisher SE, Anderson-Keightly HM, D'Elia KP, Jaworski A, TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep. 2020 Jan 28;30(4):1164-1177.e7
1	J:282827 Tulloch AJ, Teo S, Carvajal BV, Tessier-Lavigne M, Jaworski A, Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3(Cre) mouse. J Comp Neurol. 2019 Dec 15;527(18):2948-2972
1	J:268612 Vahedi-Hunter TA, Estep JA, Rosette KA, Rutlin ML, Wright KM, Riccomagno MM, Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. Sci Rep. 2018 Apr 16;8(1):5996
1*	J:248983 Varadarajan SG, Butler SJ, Netrin1 establishes multiple boundaries for axon growth in the developing spinal cord. Dev Biol. 2017 Oct 1;430(1):177-187
1	J:256148 Varadarajan SG, Kong JH, Phan KD, Kao TJ, Panaitof SC, Cardin J, Eltzschig H, Kania A, Novitch BG, Butler SJ, Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord. Neuron. 2017 May 17;94(4):790-799.e3
1	J:158549 Wang J, Wang L, Zhao H, Chan SO, Localization of an axon growth inhibitory molecule Nogo and its receptor in the spinal cord of mouse embryos. Brain Res. 2010 Jan 8;1306:8-17
1	J:251974 Wang L, Yu C, Wang J, Leung P, Ma D, Zhao H, Taylor JSH, Chan SO, Nogo-B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord. J Comp Neurol. 2017 Sep 1;525(13):2915-2928
1*	J:133488 Wolf AM, Lyuksyutova AI, Fenstermaker AG, Shafer B, Lo CG, Zou Y, Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance. J Neurosci. 2008 Mar 26;28(13):3456-67
1*	J:18717 Wolfer DP, Henehan-Beatty A, Stoeckli ET, Sonderegger P, Lipp HP, Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system. J Comp Neurol. 1994 Jul 1;345(1):1-32
1	J:272890 Wu Z, Makihara S, Yam PT, Teo S, Renier N, Balekoglu N, Moreno-Bravo JA, Olsen O, Chedotal A, Charron F, Tessier-Lavigne M, Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells. Neuron. 2019 Feb 20;101(4):635-647.e4
1	J:196985 Yam PT, Kent CB, Morin S, Farmer WT, Alchini R, Lepelletier L, Colman DR, Tessier-Lavigne M, Fournier AE, Charron F, 14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing. Neuron. 2012 Nov 21;76(4):735-49
1*	J:155069 Yam PT, Langlois SD, Morin S, Charron F, Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway. Neuron. 2009 May 14;62(3):349-62
1	J:132151 Yamauchi K, Phan KD, Butler SJ, BMP type I receptor complexes have distinct activities mediating cell fate and axon guidance decisions. Development. 2008 Mar;135(6):1119-28
1	J:314669 Yamauchi K, Varadarajan SG, Li JE, Butler SJ, Type Ib BMP receptors mediate the rate of commissural axon extension through inhibition of cofilin activity. Development. 2013 Jan 15;140(2):333-42
1*	J:276416 Zhuang M, Li X, Zhu J, Zhang J, Niu F, Liang F, Chen M, Li D, Han P, Ji SJ, The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression. Nucleic Acids Res. 2019 May 21;47(9):4765-4777